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. 2021 Nov 18;9:746646. doi: 10.3389/fchem.2021.746646

FIGURE 4.

FIGURE 4

Gas therapy-based cancer theranostics. (A) Schematic illustration of the synthesis procedure of IPH–NO. (B) The whole-body fluorescence images of 4T1 tumor-bearing mice at different time points after i.v. administration of IPH or IPH-NO. (C) Fluorescence images of the excised tumors and major organs from indicated mice at 56 h post-injection. (D) Quantification of fluorescence signals of the isolated organs and tumors. (E) Tumor growth curves in mice from different treatment groups. (F) Weight of the excised tumors in different treatment groups at day 15. *p < 0.05, **p < 0.01, ***p < 0.001. Reproduced with permission from Xu et al. (2019). Copyright 2019, Royal Society of Chemistry.