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Overviewthe KP of tryptophan metabolism. Trp, tryptophan; IDO, Indoleamine 2,3-dioxygenase; TDO, tryptophan 2,3-dioxygenase; AFMID, kynurenine formamidase; KYNU, kynureninase; KAT I–III, kynurenine amino transferases I–III; KMO, kynurenine 3-monooxygenase; HAAO, 3-hydroxyanthranilate 3,4-dioxygenase; ACMSD, α-amino-β-carboxymuconate-ε- semialdehyde decarboxylase; QPRT, quinolinic acid phosphoribosyl transferase; 5-HT, 5-Hydroxytryptophan; AADC, aromatic-l-amino acid decarboxylase.
