Table 1.
Baseline characteristics according to the ABC compliance.
| All patients | ABC group | Non-ABC group | P-value | |
|---|---|---|---|---|
| N = 19,187 | N = 43,65 | N = 14,822 | ||
| Age (years) | 64.2 ± 12.0 | 62.4 ± 11.5 | 64.7 ± 12.1 | <0.0001 |
| Age≥75, n (%) | 4,187 (21.8) | 633 (14.5) | 3,554 (24.0) | <0.0001 |
| Female, n (%) | 7,389 (38.5) | 1,500 (34.4) | 5,889 (39.7) | <0.0001 |
| SBP(mmHg) | 128.3 ± 16.6 | 120.0 ± 10.2 | 130.5 ± 17.5 | <0.0001 |
| Body mass index (kg/m2) | 25.5 ± 3.5 | 25.5 ± 3.6 | 25.5 ± 3.5 | 0.0045 |
| AF type, n (%) | ||||
| New onset | 1,179 (6.1) | 229 (5.3) | 950 (6.4) | 0.0096 |
| Paroxysmal | 10,982 (57.2) | 2,490 (57.0) | 8,492 (57.3) | |
| Persistent/permanent | 7,026 (36.6) | 1,646 (37.7) | 5,380 (36.3) | |
| eGFR <60 (CKD-EPI), n (%) | 1,876 (9.8) | 224 (5.1) | 1,652 (11.2) | <0.0001 |
| Current Smoking, n (%) | 2,253 (11.7) | 602 (13.8) | 1,651 (11.1) | <0.0001 |
| RFCA (baseline), n (%) | 8,644 (45.1) | 1,910 (43.8) | 6,734 (45.4) | 0.0506 |
| Comorbidities, n (%) | ||||
| Coronary artery disease | 2,967 (15.5) | 121 (2.8) | 2,846 (19.2) | <0.0001 |
| Peripheral arterial disease | 153 (0.8) | 10 (0.2) | 143 (1.0) | <0.0001 |
| Hypertension | 12,250 (63.9) | 2,231 (51.1) | 10,019 (67.6) | <0.0001 |
| Heart failure | 2,719 (14.2) | 187 (4.3) | 2,532 (17.1) | <0.0001 |
| Ischemic stroke or TIA | 2,774 (14.5) | 294 (6.7) | 2,480 (16.7) | <0.0001 |
| Diabetes mellitus | 4,588 (23.9) | 570 (13.1) | 4,018 (27.1) | <0.0001 |
| CHA2DS2-VASc, mean ± SD | 2.5 ± 1.8 | 1.8 ± 1.3 | 2.7 ± 1.9 | <0.0001 |
| HAS-BLED, mean ± SD | 1.8 ± 1.2 | 1.5 ± 0.9 | 1.9 ± 1.2 | <0.0001 |
| Medication, n (%) | ||||
| Warfarin | 8,186 (42.7) | 2,162 (49.5) | 6,024 (40.6) | <0.0001 |
| NOAC | 4,150 (21.6) | 749 (17.2) | 3,401 (23.0) | <0.0001 |
| ACEI/ARB | 6,531 (34.0) | 1,291 (29.6) | 5,240 (35.4) | <0.0001 |
| Beta-blocker | 8,144 (42.5) | 1,790 (41.0) | 6,354 (42.9) | 0.0288 |
| Calcium channel blocker | 852 (4.4) | 178 (4.1) | 674 (4.6) | 0.1858 |
| Statin | 7,480 (39.0) | 1,445 (33.1) | 6,035 (40.7) | <0.0001 |
| Aspirin or Clopidogrel | 4,916 (25.6) | 802 (18.4) | 4,114 (27.8) | <0.0001 |
| Insulin therapy or Oral antidiabetic drugs | 2,290 (11.9) | 309 (71) | 1,981 (13.4) | <0.00001 |
ABC, Atrial fibrillation Better Care; ACEI, angiotensin-converting-enzyme inhibitors; AF, Atrial Fibrillation; ARB, angiotensin receptor blockers; CHA2DS2-VASc, congestive heart failure, hypertension, age > 75 (doubled), diabetes mellitus, prior stroke or transient ischemic attack (doubled), vascular disease, age 65 to 74, female; eGFR, estimated glomerular filtration rate; HAS-BLED, uncontrolled hypertension, abnormal renal and/or hepatic function, stroke, bleeding history or predisposition, labile INR, elderly, drugs or excessive alcohol drinking; NOAC, non-vitamin K antagonist oral anticoagulant; SBP-systolic blood pressure; TIA, transient ischaemic attack.