Fig. 6.

In vivo therapeutic effect. (a) Schematic illustration of exogenous irradiation-free photosynthetic cyanobacteria-based photodynamic tumor therapy (n = 5). (b) Time-dependent body weights and (c) relative tumor volumes of tumor-bearing mice in different treatment groups during the therapeutic procedure, including control group, CAP + L group, Cb + L group, Cb-Vp + L group and CAP + Cb-Vp + L group. (d) Tumor volumes of mice after different treatments at day 14. (e) Individual tumor-growth curve of mice after various treatments. (f) Representative digital photos of the dissected tumors in various treatment groups. (g) H&E, Ki-67, HIF-1α and VEGF staining images of tumor sections after different treatments at day 14.