Table 1.

List of main protein components in dECM.

Protein	Distributions	Function	Reference
Collagen	The skeletal systems and most soft tissues	Provide tensile strength, connect the framework of tissue/organ, affect cell types disposition	[2,9,10]
Elastin	Most soft tissues, such as vasculature and muscle	Provide elasticity, adjust mechanical properties, increase hemocompatibility	[2,9,10]
Fibronectin	Most organs/tissues	Regulate cell behavior and function, guide branching morphogenesis in the development of complicated structures	[2,8,10]
Laminin	Cartilage, muscle	Promote cell adhesion and migration, provide bioactive sites for cross-linking	[2,8]
Matricellular Proteins	Vasculature	Contain binding sites for ECM structural proteins and cell surface receptors, and modulate activities of specific growth factors	[9]