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. 2021 Nov 16;12:768989. doi: 10.3389/fimmu.2021.768989

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Copyright © 2021 Vienne, Etiennot, Escalière, Galluso, Spinelli, Guia, Fenis, Vivier and Kerdiles

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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NKp46⁺ ILCs are dispensable for the immunosurveillance of MCA-induced tumors. Mice of the indicated genotype (A) or intravenously injected with PK136 antibody to deplete NK1.1⁺ cells (B) received a single subcutaneous injection of MCA at the indicated doses. Sarcoma formation was weekly monitored for 200 days. Tumor-bearing mice were defined as mice harboring masses increasing in size for at least two consecutive measurements. The p-values for LogRank tests are indicated.