Figure 2.

MCA-induced primary tumor cell lines with different susceptibilities to NK1.1⁺ cells. Groups of 5 C57BL/6 mice were transplanted subcutaneously with MCA-induced primary tumor cell lines, with and without treatment with a depleting anti-NK1.1 antibody. (A) Representative Kaplan-Meier curves. Mice were killed when the tumors reached a volume of 1,000 mm³. The results of LogRank tests are shown. (B) p-values and χ² of the LogRank tests associated with the survival curves of each of the primary tumor cell lines tested. One dot corresponds to one cell line. (C) Sensitivity status of the MCA-induced primary tumor cell lines as a function of the genotype of the mice receiving the MCA injection and developing the primary tumor.