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. 2021 Nov 16;12:778679. doi: 10.3389/fimmu.2021.778679

Figure 8.

Figure 8

Correlations between plasma cytokines levels at baseline, and main immune parameters of the postvaccinal response at 3 months in COVID-19-naive older subjects. The values correspond to Spearman’s rank correlation (r) coefficients. Only two correlations were found to be significant, between TNFα levels and NT50 LV-NT (r (95% CI) −0.35 [−0.62; 0.007], p = 0.048, sample size n = 33) and between TNFα levels and NT50 pV-NT (r (95% CI) −0.34 [−0.60; 0.02], p = 0.034, sample size n = 38). AIM+, cell-expressing activation-induced markers; NT50 LV-NT assay, 50% serum neutralization titer in live virus neutralization assay; NT50 PV-NT assay, 50% serum neutralization titer in pseudovirus neutralization assay.