Table 1.
Baseline characteristics of study patients after 1:1 matching.
| Variable | Patients with osteoarthritis (N = 130,112) | Patients without osteoarthritis (N = 130,112) | P-value |
|---|---|---|---|
| Sex | |||
| Female | 80,687 (62.0) | 80,687 (62.0) | 1.000 |
| Male | 49,425 (38.0) | 49,425 (38.0) | |
| Age (in years) | |||
| Mean (standard deviation) | 66.4 (12.7) | 66.4 (12.7) | 1.000 |
| ≤50 | 14,544 (11.2) | 14,544 (11.2) | 1.000 |
| 51–60 | 31,170 (24.0) | 31,170 (24.0) | |
| 61–70 | 34,217 (26.3) | 34,217 (26.3) | |
| 71–80 | 30,047 (23.1) | 30,047 (23.1) | |
| >80 | 20,134 (15.4) | 20,134 (15.4) | |
| Disorders documented prior to or on the index date | |||
| Hypertension | 42,170 (32.4) | 36,776 (28.3) | <0.001 |
| Diabetes mellitus | 12,114 (9.3) | 10,660 (8.2) | <0.001 |
| Thyroid diseases | 11,781 (9.1) | 9,760 (7.5) | <0.001 |
| Dyslipidemia | 11,031 (8.5) | 9,240 (7.1) | <0.001 |
| Coronary heart disease | 8,972 (6.9) | 6,347 (4.9) | <0.001 |
| Gout | 5,952 (4.6) | 4,601 (3.5) | <0.001 |
| Chronic obstructive pulmonary disease | 5,865 (4.5) | 5,339 (4.1) | <0.001 |
| Stroke including transient ischemic attack | 5,759 (4.4) | 5,964 (4.6) | 0.053 |
| Intracranial injury | 1,811 (1.4) | 2,015 (1.5) | 0.009 |
Data are N (%) unless otherwise specified.