Table 2.
Statistical results of univariate analysis.
| Variable | Statistics (r/U/F) | p-value |
|---|---|---|
| Risperidone dose | 0.360 | <0.001 |
| The initial TDM | 0.624 | <0.001 |
| TDM interval | 0.041 | 0.203 |
| Age | −0.113 | <0.001 |
| Height | 0.005 | 0.865 |
| Weight | 0.023 | 0.469 |
| BMI | 0.024 | 0.456 |
| PLT | 0.073 | 0.024 |
| WBC | 0.106 | <0.001 |
| RBC | 0.041 | 0.207 |
| BUN | 0.008 | 0.798 |
| Cr | 0.039 | 0.002 |
| Ccr | 0.048 | 0.141 |
| PRL | 0.061 | 0.116 |
| AST | −0.020 | 0.536 |
| ALT | 0.020 | 0.541 |
| Sex | 113229.5 | 0.123 |
| MECT | 88230.0 | 0.003 |
| Haloperidol | 84488.0 | 0.158 |
| Other_CYP2D6 enzyme inhibitors | 86395.0 | 0.177 |
TDM, therapeutic drug monitoring; BMI, body mass index; PLT, platelet; RBC, red blood cells; WBC, white blood cells; BUN, blood urea nitrogen; Cr, serum creatinine; Ccr, creatinine clearance rate; ALT, alanine transaminase; AST, aspartate transaminase; PRL, prolactin; MECT, modified electroconvulsive therapy.