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. 2021 Nov 18;12:711868. doi: 10.3389/fpsyt.2021.711868

Table 3.

The importance score of variables in XGBoost.

Variables Importance score
The initial TDM 0.2522
Risperidone dose 0.0616
Ccr 0.0598
Weight 0.0592
BUN 0.057
WBC 0.0527
Height 0.0522
ALT 0.0512
PLT 0.0457
MECT 0.0394
AST 0.0394
Haloperidol 0.0381
RBC 0.0367
Cr 0.0366
PRL 0.0341
BMI 0.0327
Age 0.0279
TDM interval 0.0235
Sex 0
Other_CYP2D6 enzyme inhibitors 0

TDM, therapeutic drug monitoring; BMI, body mass index; PLT, platelet; RBC, red blood cells; WBC, white blood cells; BUN, blood urea nitrogen; Cr, serum creatinine; Ccr, creatinine clearance rate; ALT, alanine transaminase; AST, aspartate transaminase; PRL, prolactin; MECT, modified electroconvulsive therapy.