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. 2021 Nov 18;12:722421. doi: 10.3389/fgene.2021.722421

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Copyright © 2021 Zhang, Li, Zhang, Wang, Yang, Shao, Liang, Ma, Zhang, Jing, Song and Fan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The TME characteristics were correlated with clinical features in ccRCC patients. (A–C) The Kaplan–Meier analysis was generated to display the survival significances of different groups stratified by the median value of the immune score (A), stromal score (B), and estimate score (C). (D–F) Distribution of the immune score (D), stromal score (E), and estimate score (F) in the different stages. (G–I) Distribution of the immune score (G), stromal score (H), estimate score (I) in the different T classifications. TME, tumor microenvironment; ccRCC, clear cell renal cell carcinoma.