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. 2021 Nov 16;12:745987. doi: 10.3389/fneur.2021.745987

Table 2.

Values of the phase differences of phasors of deoxyhemoglobin (D) vs. arterial blood pressure (ABP), oxyhemoglobin (O) vs. ABP, total hemoglobin (T) vs. ABP, normalized cerebral blood flow (cbf) vs. normalized arterial blood pressure (abp), and D vs. O during normocapnia and hypercapnia.

Phase difference (°)
Normocapnia (NC) Hypercapnia (HC) HC − NC p-values
D/ABP SDI −214 [−225, −195] −259 [−323, −237] −50 ± 33 0.003** (n = 8)
SDϕ −208 [−219, −204] −248 [−252, −234] −34 ± 19 0.0003*** (n = 9)
SSI −211 [−235, −193] −263 [−292, −239] −59 ± 41 0.001** (n = 10)
DSI −211 [−227, −200] −263 [−285, −233] −56 ± 38 0.02* (n = 5)
DSϕ −211 [−217, −199] −225 [−241, −220] −21 ± 12 0.005** (n = 5)
O/ABP SDI −37 [−51, −21] −53 [−64, −36] −14 ± 12 0.001** (n = 10)
SDϕ −18 [−42, 3] −50 [−62, −30] −33 ± 23 0.002** (n = 9)
SSI −28 [−43, −7] −53 [−68, −34] −26 ± 26 0.02* (n = 9)
DSI −28 [−48, −2] −63 [−66, −34] −27 ± 24 0.03* (n = 5)
DSϕ 42 [24, 49] −42 [−87, 1] −78 ± 38 0.01* (n = 4)
T/ABP SDI −47 [−68, −30] −43 [−61, −31] −1 ± 8 0.4 (n = 10)
SDϕ −10 [−34, 17] −30 [−43, −19] −22 ± 26 0.02* (n = 8)
SSI −21 [−45, 7] −42 [−55, −27] −17 ± 27 0.09 (n = 9)
DSI −27 [−49, 8] −28 [−56, −24] −17 ± 17 0.04* (n = 5)
DSϕ 109 [62, 129] 83 [5, 114] −20 ± 49 0.2 (n = 5)
cbf/abp SDI 8 [−4, 27] −22 [−39, 1] −29 ± 19 0.0006** (n = 10)
SDϕ 16 [−5, 39] −15 [−34, 2] −34 ± 26 0.006** (n = 9)
SSI 10 [−4, 32] −20 [−54, −2] −40 ± 34 0.006** (n = 9)
DSI 12 [−7, 34] −34 [−37, −1] −36 ± 24 0.01* (n = 5)
DSϕ 30 [23, 41] −22 [−31, 8] −46 ± 24 0.006** (n = 5)
D/O SDI −181 [−190, −149] −207 [−250, −205] −44 ± 30 0.004** (n = 8)
SDϕ −193 [−197, −185] −197 [−206, −189] −1 ± 9 0.4 (n = 9)
SSI −186 [−187, −179] −199 [−212, −193] −26 ± 26 0.03* (n = 8)
DSI −181 [−189, −179] −201 [−203, −199] −16 ± 5 0.0007*** (n = 4)
DSϕ −242 [−254, −232] −192 [−220, −152] 56 ± 31 0.5 (n = 4)

Values are reported as median [25%, 75% quartiles] for phase measurements at normocapnia and hypercapnia. The differences in the phase values between hypercapnia and normocapnia are shown as means ± standard deviations. p-values from statistical test on angular means are shown and indicated in red color for significant values; * for p < 0.05; ** for p < 0.01; and *** for p < 0.001.