Table 2.

Mann-Whitney U tests comparing the median fasting gastrin concentrations between groups.

Group comparison		Median	Difference between medians		p-value	Adjusted p value~
Group 1	Group 2	Group 1: Group 2	Actual difference	Hodges-Lehmann adjusted difference
Normal group	All PPI users	20: 46	26	24	<0.0001	<0.0001
	Standard dose PPI users	20: 46	26	24	<0.0001	<0.0001
	High dose PPI users	20: 72	52	42	<0.0001	<0.0001
	Low dose PPI users	20: 31	11	11	0.0012	0.0300
	All active H. pylori	20: 32	12	12	<0.0001	<0.0001
	Active H. pylori with PPI	20: 50	30	27	<0.0001	<0.0001
	Active H. pylori without PPI	20: 27	7	7	<0.0001	<0.0001
	Antrum preneoplasia with PPI	20: 53	33	28	<0.0001	<0.0001
	Antrum preneoplasia without PPI	20: 25	5	6	<0.0001	0.0018
	Corpus preneoplasia with PPI	20: 90	70	68	<0.0001	<0.0001
	Corpus preneoplasia without PPI	20: 48	28	27	<0.0001	<0.0001
All PPI users	Active H. pylori without PPI	46: 27	19	16	<0.0001	<0.0001
	Active H. pylori with PPI	46: 50	4	7	0.1273	>0.999
	Antrum preneoplasia with a PPI	46: 53	7	6	0.1568	>0.999
	Antrum preneoplasia without a PPI	46: 25	21	16	<0.0001	<0.0001
	Corpus preneoplasia with a PPI	46: 90	44	36	<0.0001	0.0007
	Corpus preneoplasia without a PPI	46: 48	2	8	0.1765	>0.999
Standard dose PPI users	High dose PPI users	46: 72	26	14	0.0755	>0.999
	Low dose PPI users	46: 31	15	12	0.0669	>0.999
High dose PPI users	Low dose PPI users	72: 31	41	26	0.0197	0.4925
H. pylori with PPI	H. pylori without PPI	50: 27	23	21	<0.0001	<0.0001
Antrum preneoplasia with PPI	Antrum preneoplasia without PPI	53: 25	28	20	<0.0001	<0.0001
	Corpus preneoplasia with PPI	53: 90	37	26	0.0129	0.0645
Corpus preneoplasia without PPI	Corpus preneoplasia with PPI	48: 90	42	13	0.2617	>0.999
	Antrum preneoplasia without PPI	48: 25	23	20	0.0002	0.005

~p values were adjusted using the Bonferroni correction for multiple comparisons.

Bold values are statistically significant.