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. 2021 Dec 1;158(1):1–9. doi: 10.1001/jamadermatol.2021.4918

Table 2. Association of Psoriasis With Venous Thromboembolism According to Subgroups.

Subgroups Venous thromboembolism Subgroup differences
No. of studies Pooled HR (95% CI) P value I2 (%) P value I2 (%)
Arthritis status
Psoriasis alone 2 0.97 (0.78-1.21) .79 89 .11 61.2
Psoriatic arthritis 3 1.24 (1.01-1.53)a .04 82
Psoriasis severity
Mild psoriasis 1 1.07 (1.03-1.12)a .002 NA .45 0
Severe psoriasis 1 1.13 (0.99-1.30) .08 NA
Sex
Men 2 1.40 (0.90-2.19) .13 93 .29 9.2
Women 3 1.89 (1.36-2.61)a <.001 84
Geographic location
US 2 1.07 (0.67-1.70) .78 86 .04 68.3
Asia 1 2.02 (1.42-2.88)a <.001 NA
Europe 4 1.28 (1.06-1.53)a .01 95

Abbreviations: HR, hazard ratio; NA, not applicable.

a

P < .05.