Fig. 3.

Surface TRAIL changes upon encounter with colon cancer cells. (A) Representative dot plots for iNKT cells prior and after coculture. (B–C) Fold change of TRAIL‐positive intestinal (B) and blood‐derived (C) iNKT cells respect to resting conditions. D‐E. TRAIL receptor 1 (TRAILR1, D) and TRAIL receptor 2 (TRAILR2, E) expression in colorectal cancer (CRC) cell lines. Kruskal–Wallis test was used to assess statistical significance, and Dunn’s test was used for multiple comparisons in B‐C. ns. nonsignificant, P‐value < 0.05 (*), 0.01 (**), 0.001 (***), 0.0001 (****). Data are means ± SD of at least 3 independent experiments in B and C.