Table 5. Solvent accessible surface area referring the area to energy ratio over the entire dynamic simulation process (100 nanoseconds) with polar and apolar regions precisely.
| Macromolecule | Ligands | WPR (Å) | GIC | TNR | Total area/energy (Ų/[kcal·mol]) | ||
| Polar | Apolar | Unknown | |||||
| WPR: water probe radius; GIC: gradient in calculation; TNR: total No. of residues. | |||||||
| α-DG | Nobiletin | 1.4 | No | 244 | 4620.04 | 7575.65 | 0.00 |
| α-DG | Reticuline | 1.4 | No | 244 | 4620.04 | 7575.65 | 0.00 |
| α-DG | Kirenol | 1.4 | No | 244 | 4620.04 | 7575.65 | 0.00 |
| α-DG | Chrysin | 1.4 | No | 244 | 4620.04 | 7575.65 | 0.00 |
| α-DG | 3-caffeoylshikimic acid | 1.4 | No | 244 | 4620.04 | 7575.65 | 0.00 |
| α-DG | Gigantamide A | 1.4 | No | 244 | 4620.04 | 7575.65 | 0.00 |
| α-DG | Dasyclamide | 1.4 | No | 244 | 4620.04 | 7575.65 | 0.00 |