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. 2021 Nov 27;13(11):1688–1698. doi: 10.4254/wjh.v13.i11.1688

Table 4.

Non-alcoholic fatty liver disease spectrum

Non-alcoholic fatty liver disease spectrum
NAFL Steatosis changes. No cellular ballooning, hepatocyte inflammation or fibrosis Prevalence of 25% approximately. Reversible
NASH Steatosis changes. Cellular ballooning and hepatocyte inflammation. No fibrosis Prevalence of 1.5%-6.45% approximately. Generally irreversible (has been found to be reversible in some patients)
NASH related liver cirrhosis Hepatocyte destruction and fibrosis Prevalence of 1%-2% approximately. Irreversible
Healthy liver ←→ NAFL → NASH → NASH related cirrhosis

NAFL: Non-alcoholic fatty liver; NASH: Non-alcoholic steatohepatitis.