Table 4.
Non-alcoholic fatty liver disease spectrum
| ||
NAFL | Steatosis changes. No cellular ballooning, hepatocyte inflammation or fibrosis | Prevalence of 25% approximately. Reversible |
NASH | Steatosis changes. Cellular ballooning and hepatocyte inflammation. No fibrosis | Prevalence of 1.5%-6.45% approximately. Generally irreversible (has been found to be reversible in some patients) |
NASH related liver cirrhosis | Hepatocyte destruction and fibrosis | Prevalence of 1%-2% approximately. Irreversible |
Healthy liver ←→ NAFL → NASH → NASH related cirrhosis |
NAFL: Non-alcoholic fatty liver; NASH: Non-alcoholic steatohepatitis.