Table 1.
Comparison of demographic data for patients hospitalized with Clostridioides difficile infection with coexisting nonalcoholic fatty liver disease, viral liver disease and alcoholic liver disease
|
Variables
|
CDI with NAFLD
|
CDI with VLD
|
CDI with ALD
|
P
value
|
|
|
n
(weighted)
|
7239
|
11857
|
5938
|
CDI with NAFLD vs CDI with VLD
|
CDI with NAFLD vs CDI with ALD
|
| Age (yr) | 56.32 ± 0.42 | 57 ± 0.26 | 56.13 ± 0.37 | 0.15 | 0.73 |
| 18-39 | 1133 (15.6%) | 791 (6.7%) | 557 (9.4%) | < 0.0001 | < 0.0001 |
| 40-49 | 1290 (17.8%) | 1811 (15.3%) | 1051 (17.7%) | ||
| 50-59 | 1618 (22.4%) | 4873 (41.1%) | 2021 (34%) | ||
| 60-69 | 1620 (22.4%) | 2791 (23.5%) | 1439 (24.2%) | ||
| ≥ 70 | 1578 (21.8%) | 1591 (13.4%) | 870 (14.7%) | ||
| Sex | < 0.0001 | < 0.0001 | |||
| Female | 5023 (69.4%) | 5795 (48.9%) | 2300 (38.7%) | ||
| Race | < 0.0001 | 0.17 | |||
| Caucasian | 5427 (75%) | 6920 (58.4%) | 4358 (73.4%) | ||
| African American | 482 (6.5%) | 2773 (23.4%) | 525 (8.8%) | ||
| Hispanic | 648 (9%) | 1144 (9.6%) | 515 (8.7%) | ||
| Hospital bed size | 0.033 | 0.9 | |||
| Large | 4241 (58.6%) | 7414 (62.6%) | 3461 (58.3%) | ||
| Hospital region | < 0.0001 | < 0.0001 | |||
| Northeast | 1091 (15.1%) | 2618 (22.1%) | 1243 (20.9%) | ||
| Midwest | 1618 (22.3%) | 2514 (21.1%) | 1584 (26.7%) | ||
| South | 3008 (41.6%) | 4208 (35.5%) | 1671 (28.1%) | ||
| West | 1522 (21%) | 2517 (21.2%) | 1440 (24.3%) | ||
| Hospital type | < 0.0001 | 0.22 | |||
| Urban teaching | 3401 (47%) | 7207 (60.8%) | 3065 (51.6%) | ||
| Insurance | < 0.0001 | < 0.0001 | |||
| Medicare | 3086 (42.6%) | 5493 (46.3%) | 2239 (37.7%) | ||
| Medicaid | 914 (12.6%) | 3329 (28.1%) | 1261 (21.2%) | ||
| Private | 2526 (34.9%) | 1835 (15.5%) | 1391 (23.4%) | ||
| Median household income for ZIP Code, % | < 0.0001 | 0.61 | |||
| Q1 | 1790 (24.7%) | 4205 (35.5%) | 1592 (26.8%) | ||
| Q2 | 1824 (25.2%) | 3128 (26.4%) | 1407 (23.7%) | ||
| Q3 | 1926 (26.6%) | 2353 (19.8%) | 1503 (25.3%) | ||
| Q4 | 1511 (20.9%) | 1657 (14%) | 1252 (21.1%) | ||
Values reported as weighted mean ± SE and weighted number [n (%)]. CDI: Clostridioides difficile infection; NAFLD: Nonalcoholic fatty liver disease; VLD: Viral liver disease; ALD: Alcoholic liver disease; Q1: Quartile 1, 0-25th percentile; Q2: Quartile 2, 26th-50th percentile; Q3: Quartile 3, 51th-75th percentile; Q4: Quartile 4, 76th-100th percentile.