TABLE 1.
MODS sensitivity and time to detection of MTB versus standard culture methods
| Method | No. of samples positive by method | No. of samples positive by at least one culturea | Sensitivity (%)b | Median detection time (range)c |
|---|---|---|---|---|
| Auramine O stain | 76 | 98 | 78 | |
| MODS | 89 | 97 | 92 | 9 (4–31) |
| MGIT | 88 | 95 | 93 | 10 (4–39) |
| LJ | 73 | 96 | 76 | 24 (6–59) |
| microagar 7H11 | 75 | 96 | 78 | 14.5 (4–28) |
| PCR | 81 | 90 | 90 |
a
Only samples which were positive by at least one culture (MODS, MGIT, LJ, or 7H11) and interpretable by the given method were considered in determining sensitivity. Of the 172 samples, 98 were positive by at least one culture. Denominators differ for different methods because not all results were interpretable due to contamination or (in the case of PCR) insufficient patient sample.
b
Sensitivity is based on the gold standard of detection by any culture.
c
Includes only interpretable results. Values shown are in days.