Table 2.

Core clinical characteristics of seropositive and seronegative NMOSD.

Clinical characteristics	AQP4-IgG positive NMOSD (n = 41)	MOG-IgG positive NMOSD (n = 7)	AQP4 and MOG-IgG negative NMOSD (n = 3)
LETM	28 (68%)	6 (86%)	3 (100%)
Optic Neuritis	14 (34%)	6 (86%)	2 (67%)
Area Postrema syndrome	8 (20%)	0	0
Other Brainstem syndrome	0	1 (14%)	1 (33%)
Symptomatic cerebral syndrome	1 (2%)	4 (57%)	0
Symptomatic narcolepsy	0	0	0

Abbreviations: AQP4-IgG, Aquaporin-4-IgG; LETM, Longitudinally extensive transverse myelitis; MOG-IgG, myelin oligodendrocyte glycoprotein-IgG; NMOSD, Neuromyelitis optica spectrum disorder.