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. 2021 Nov 18;12:791322. doi: 10.3389/fphar.2021.791322

TABLE 2.

Univariate and multivariate analyses for risk factors associated with PHLF.

Variable Hazard ratio (95% CI) p Value
PCT (≥1 vs. <1 ng/ml) 5.064 (2.485, 10.319) <0.001
PCT* 1.092 (1.057, 1.129) <0.001
Sex (male vs. female) 0.435 (0.153, 1.240) 0.119
Age (year) 0.989 (0.964, 1.015) 0.414
Hypertension 1.059 (0.659, 1.703) 0.812
DM 1.353 (0.552, 3.316) 0.509
Smoking history 1.025 (0.465, 2.262) 0.951
Drinking history 1.729 (0.777, 3.843) 0.179
Surgical history 0.68 (0.159, 2.901) 0.602
Cirrhosis 2.45 (1.225, 4.900) 0.011
Portal hypertension 3.053 (1.576, 5.913) 0.001
Ascites 2.115 (0.944, 4.739) 0.069
Tumor number (multiple vs single) 3.664 (1.886, 7.117) <0.001
Tumor size (>5 vs. ≤5, cm) 1.066 (0.56, 2.030) 0.845
Portal blocking time (>30 vs. ≤30, min) 2.563 (1.334, 4.922) 0.005
Blood loss (>500 vs. ≤500, ml) 3.921 (2.048, 7.508) <0.001
Blood transfusion (>200 vs. ≤200, ml) 5.677 (2.919, 11.041) <0.001
Liver resection (≥3 vs. <3 segment) 1.784 (0.941, 3.380) 0.076
Antivirus 0.607 (0.292, 1.262) 0.182
HBV DNA (≥50 vs. <50 IU/ml) 1.216 (0.64, 2.312) 0.55

The bold values represent the statistical significance of the data.