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. 2021 Nov 17;8:733343. doi: 10.3389/fsurg.2021.733343

Table 2.

Univariate analysis of categorical variables.

Variable Total MVI– MVI+ p
(n = 642) (n = 377) (n = 265)
Sex Female 522 (81.31) 302 (80.11) 220 (83.02) 0.351
Male 120 (18.69) 75 (19.89) 45 (16.98)
Edmondson-Steiner grade I/II 421 (65.68) 293 (77.72) 128 (48.48) <0.001
III/IV 220 (34.32) 84 (22.28) 136 (51.52)
Liver capsule invasion Absent 323 (50.47) 223 (59.47) 100 (37.74) <0.001
Present 317 (49.53) 152 (40.53) 165 (62.26)
Number of tumors Single 569 (88.77) 337 (89.63) 232 (87.55) 0.494
≥2 72 (11.23) 39 (10.37) 33 (12.45)
Satellite nodules Absent 560 (87.50) 344 (91.49) 216 (81.82) <0.001
Present 80 (12.50) 32 (8.51) 48 (18.18)
Cirrhosis Absent 216 (33.70) 126 (33.51) 90 (33.96) 0.905
Present 425 (66.30) 250 (66.49) 175 (66.04)
BDTT Absent 623 (97.50) 375 (99.73) 248 (94.30) <0.001
Present 16 (2.50) 1 (0.27) 15 (5.70)
Surgical options Open 419 (65.47) 249 (66.05) 170 (64.64) 0.712
Laparoscope 221 (34.53) 128 (33.95) 93 (35.36)
AFP, ng/ml ≤400 469 (73.28) 297 (79.20) 172 (64.91) <0.001
>400 171 (26.72) 78 (20.80) 93 (35.09)
HBsAg Negative 109 (17.06) 59 (15.73) 50 (18.94) 0.289
Positive 530 (82.94) 316 (84.27) 214 (81.06)

MVI, microvascular invasion; BDTT, bile duct tumor thrombus; AFP, alpha-fetoprotein; HBsAg, type B hepatitis surface antigen.