Table 1.
Clinical and biological characteristics of BC patients.
| Number of patients (977) | Modena | Lecce | p-Value |
|---|---|---|---|
| 470 | 507 | ||
| Mean age at diagnosis (year) | 61.42 (28–88); SD 12.48 | 62.08 (28–97); SD 13.65 | 0.461 |
| Age group (year) | |||
| <40 | 19 (4%) | 22 (4.3%) | 0.315 |
| 40–49 | 75 (16%) | 91 (18%) | |
| 50–69 | 234 (49.8%) | 222 (43.8%) | |
| >70 | 142 (30.2%) | 172 (33.9%) | |
| ER | |||
| Negative (0) | 70 (15.4%) | 84 (16.9%) | 0.571 |
| Positive (≥1) | 385 (84.6%) | 414 (83.1%) | |
| PgR | |||
| Negative (0) | 91 (21.4%) | 128 (25.8%) | 0.114 |
| Positive (≥1) | 335 (78.6%) | 368 (74.2%) | |
| HER2 | |||
| Negative | 387 (85.1%) | 432 (88.5%) | 0.116 |
| Positive | 68 (14.9%) | 56 (11.5%) | |
| Proliferation index | |||
| Low | 281 (64.9%) | 294 (59.3%) | 0.078 |
| High | 152 (35.1%) | 202 (40.7%) | |
| pT | |||
| pT1 | 303 (81.2%) | 308 (83.3%) | 0.139 |
| ≥pT2 | 70 (18.8%) | 53 (14.7%) | |
| pN | |||
| pN0 | 261 (70.5%) | 261 (66.6%) | 0.240 |
| ≥pN1 | 109 (29.5%) | 131 (33.4%) | |
| Mean diameter (cm) | 1.57 (0.01–18); SD 1.57 | 1.68 (0.10–9.9); SD 1.50 | <0.001 |
ER, estrogen receptor; PgR, progesteron receptor; HER2, human epidermal growth factor receptor-2; pT, pathological tumor size; pN, pathological lymph nodes; SD, stardard deviation.