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. 2021 Nov 17;12:766391. doi: 10.3389/fimmu.2021.766391

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Copyright © 2021 Pan, Li, Liu, Wang, Huang and Ouyang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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All CitH3 concentration is elevated in septic AP patients and may be a reliable diagnostic biomarker of sepsis in AP. Blood samples from SP, NIP, and HV groups were collected. CitH3 and PCT concentration were measured by ELISA kit. CitH3 concentration was increased significantly in the SP group compared with that in the HV and NIP groups (A). No significant differences in PCT concentration were identified among SP, NIP, and HV groups (B). Receiver operating characteristic curves analysis of CitH3 and PCT to diagnose septic AP compared with that of the HV (C) and NIP group (D). Detailed information of receiver operating characteristic curve analysis is presented in the table (E). ^* p < 0.05; ns, non-significant.