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. 2021 Nov 17;12:766391. doi: 10.3389/fimmu.2021.766391

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Copyright © 2021 Pan, Li, Liu, Wang, Huang and Ouyang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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All CitH3 may be a promising prognostic biomarker in septic AP patients. AP patients were subgrouped into survival and death groups (A) or ICU (cases admitted into ICU) and non-ICU (cases not admitted into ICU) groups (C). Concentration of CitH3 was measured by ELISA. Levels of CitH3 were increased significantly in the death group and ICU group compared with those in survival group and non-ICU group, respectively. Receiver operating characteristic curve analysis of CitH3 to distinguish survival and death cases (B) and cases admitted or not into ICU (D). The detailed information of receiver operating characteristic curve analysis is presented in the table (E). ^* p < 0.05.