Table 1.
Baseline demographics and clinical characteristics for septic AP patients and noninfectious AP patients.
| Variables | SP (n = 40) | NIP (n = 30) | HV (n = 30) | p-value |
|---|---|---|---|---|
| Age (mean (SD)) | 47.3 (12.37) | 55.8 (10.76) | 50.9 | >0.05 |
| Female (n (%)) | 8 (20) | 8 (26.7) | 9 (30) | >0.05 |
| PCT (ng/ml, median (IQR)) | 0.43 (0.17–0.99) | 0.27 (0.2–0.8) | 0 (0–0.08) | >0.05 |
| Lactate (mmol/L, median (IQR)) | 2 (1.8–2.4) | 1.6 (1.3–1.9) | <0.05 | |
| CitH3 (pg/ml, median (IQR)) | 127.3 (82.4–210.2) | 27.5 (21–33.5) | 26.5 (20.5–39.75) | <0.05 |
| PAD2 (ng/ml, median (IQR)) | 3.03 (2.1–3.68) | 0.32 (0.21–0.49) | 0.16 (0.1–0.26) | <0.05 |
| PAD4 (ng/ml, median (IQR)) | 3.11 (2.53–4.71) | 0.28 (0.14–0.51) | 0.12 (0.07–0.21) | <0.05 |
| dsDNA (ng/ml, median (IQR)) | 913.5 (812–1063) | 257 (232.5–294) | 89 (65–100) | <0.05 |
| Survivals (n (%)) | 33 (82.5) | 30 (100) | <0.05 | |
| Length of hospital stay (day, median (IQR)) | 28.5 (20.8–57) | 13.5 (11.3–16.8) | <0.05 | |
| Length of ICU stay (day, median (IQR)) | 4 (1–7.25) | 0 (0–0) | <0.05 | |
| Total SOFA score (median (IQR)) | 5 (3–8) | 1 (1–2) | <0.05 | |
| Respiratory SOFA (median (IQR)) | 2 (2–3) | 1 (1–2) | <0.05 | |
| Renal SOFA (median (IQR)) | 1 (0–3) | 0 (0–0) | <0.05 | |
| Cardiovascular SOFA (median (IQR)) | 0 (0–0) | 0 (0–0) | <0.05 | |
| Neurologic SOFA (median (IQR)) | 0 (0–0) | 0 (0–0) | <0.05 | |
| Hepatic SOFA (median (IQR)) | 1 (0–1) | 0 (0–0) | <0.05 | |
| Coagulation SOFA (median (IQR)) | 0 (0–1) | 0 (0–0) | <0.05 |
Categorical variables are shown as number (%). For continuous variables, normally distributed values are shown as mean (SD) while not normally distributed are shown as median (interquartile range Q1/Q3). AP, acute pancreatitis; PCT, procalcitonin; CitH3, citrullinated histone H3; PAD2/4, peptidylarginine deiminase 2/4; ICU, intensive care unit; SOFA, sequential organ failure assessment.