Table 4.

The proportion (%) of CD4+ lymphocytes in patients with 18q del, patients with T1D (control group), and 28 healthy controls.

	18q del (n = 24)	T1D (n = 24)	Control (n = 28)	p-value in ANOVA
T subsets (%)
CD4+
Median	21.82	54.27	40.50
Mean (min–max)	22.87 (4.42–50.59)	56.94 (43.93–78.9)	40.94 (24.07–56.12)	<0.0001
SD	11.42	10.47	7.61
Tnaive
Median	62.49	63.02	53.85
Mean (min–max)	58.54 (28.31–82.55)	62.08 (19.88–82.93)	50.08 (11.67–58.68)	<0.0003
SD	14.66	15.52	16.68
Tcm
Median	23.82	24.29	30.32
Mean (min–max)	25.37 (12.35–37.6)	22.91 (6.65–39.18)	32.91 (17.00–58.68)	<0.0001
SD	7.32	9.25	11.15
Tem
Median	9.8	7.08	13.96
Mean (min–max)	9.8 (2.08–28.4)	8.091 (2.87–18.71)	32.91 (17.00–58.68)	<0.0001
SD	6.97	4.261	11.15
Treg FOXP3+
Median	2.2	4.88	6.00
Mean (min–max)	2.91 (0.5–8.96)	5.26 (2.35–9.24)	5.95 (2.30–9.40)	<0.0001
SD	2.03	1.73	1.99
Treg FOXP3+Helios+
Median	6.41	73.59	78.54
Mean (min–max)	9.17 (2.86–31.89)	75.27 (36.92–95.39)	78.65 (56.66–97.11)	<0.0001
SD	7.616	12.73	11.09