Table 1.
The epidemiological and clinical characteristics of the patients undergoing IVF/PGT treatment.
| Characteristic | Implanted N=131 | Non-implanted N=185 | p value |
|---|---|---|---|
| Maternal age, y, mean ± SD | 32.1 ± 4.7 | 33.2 ± 4.7 | 0.050 |
| paternal age, y, mean ± SD | 34.5 ± 5.9 | 34.5 ± 5.2 | 0.733 |
| BMI, kg/m2, mean ± SD | 21.4 ± 2.4 | 21.6 ± 2.4 | 0.277 |
| Education, n (%) | 0.911 | ||
| Senior high school degree or less | 19 (38.8) | 30 (61.2) | |
| college degree | 97 (41.8) | 135 (58.2) | |
| post-graduate degree | 15 (42.9) | 20 (57.1) | |
| gravidity | 1 (0-2) | 0 (0-2) | 0.248 |
| parity | 0 (0-0) | 0 (0-0) | 0.483 |
| Cycle protocols, n (%) | 0.896 | ||
| GnRH agonist protocol | 51 (41.8) | 71 (58.2) | |
| Antagonist protocol | 70 (41.9) | 97 (58.1) | |
| microdose flare protocol | 9 (40.9) | 13 (59.1) | |
| Other protocol | 1 (20.0) | 4 (80.0) | |
| Indications for PGT, n (%) | 0.861 | ||
| chromosomal abnormalities | 44 (40.7) | 64 (59.3) | |
| Advanced age | 16 (37.2) | 27 (62.8) | |
| Male factor | 19 (45.2) | 23 (54.8) | |
| Recurrent implantation failure | 6 (42.9) | 8 (57.1) | |
| Recurrent miscarriage | 21 (48.8) | 22 (51.2) | |
| Patient request | 25 (37.9) | 41 (62.1) | |
| Infertility type, n (%) | 0.400 | ||
| Primary | 47 (44.8) | 58 (55.2) | |
| Secondary | 84 (39.8) | 127 (60.2) | |
| bFSH, IU/L | 7.1 ± 2.2 | 7.3 ± 2.4 | 0.377 |
| bLH, IU/L | 5.0 ± 2.5 | 4.5 ± 2.1 | 0.164 |
| bEstradiol, pmol/L | 144.5 ± 75.5 | 140.5 ± 66.0 | 0.800 |
| gonadotropin duration, days | 10.0 ± 2.6 | 9.8 ± 2.3 | 0.741 |
| Gonadotropin dosage, IU | 2326.5 ± 725.6 | 2359.0 ± 738.0 | 0.626 |
| endometrial thickness, mm | 9.4 ± 1.5 | 9.4 ± 1.5 | 0.914 |
| FET type, n (%) | 0.444 | ||
| Natural cycle | 42 (38.5) | 67 (61.5) | |
| HRT cycle | 89 (43.0) | 118 (57.0) | |
| Biopsy day, n (%) | 0.019* | ||
| 5 | 38 (53.5) | 33 (46.5) | |
| 6 | 93 (38.0) | 152 (62.0) | |
| TE quality, n (%) | 0.136 | ||
| A | 6 (60.0) | 4 (40.0) | |
| B | 91 (44.0) | 116 (56.0) | |
| C | 34 (34.3) | 65 (65.7) | |
| ICM quality, n (%) | 0.068 | ||
| A | 20 (55.6) | 16 (44.4) | |
| B | 111 (39.6) | 169 (60.4) | |
| C | 0 (0) | 0 (0) | |
| Blastocyst quality, n (%) | 0.078 | ||
| Good | 20 (55.6) | 16 (44.4) | |
| Average | 77 (42.5) | 104 (57.5) | |
| Poor | 34 (34.3) | 65 (65.7) |
Continuous variables were calculated by Mann-Whitney test, categorical variables were calculated by chi-squared test; BMI, body mass index; PGT, preimplantation genetic testing; TE, Trophectoderm; ICM, inner cell mass; bLH, basic luteinizing hormone; bFSH, basic follicle-stimulating hormone; bAMH, basic anti-Müllerian hormone; FET, frozen-thawed embryo transfer; HRT, hormone replacement therapy; *p<0.05.