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. 2021 Nov 18;6(47):32043–32071. doi: 10.1021/acsomega.1c04817

Table 2. Shortlisted CTL Epitopes for the Final Vaccine Construction.

epitopes protein C-score immunogenicity score antigenicity allergenicity toxicity epitope conservancy hit (maximum identity %) human homology interacting MHC-I allelesa
GSNDTELNY L 2.1551 0.13913 (positive) 1.1545 (probable antigen) probable non-allergen non-toxin 100 non-homologue HLA-A*01:01, HLA-B*58:01, HLA-A*30:02
WTIGNRAPY L 2.4674 0.14626 (positive) 1.2809 (probable antigen) probable non-allergen non-toxin 100 non-homologue HLA-A*26:01, HLA-A*30:02, HLA-A*01:01, HLA-C*03:03, HLA-B*15:01, HLA-B*35:01
FDERRHVAM NP 2.2254 0.22313 (positive) 0.9841 (probable antigen) probable non-allergen non-toxin 100 non-homologue HLA-B*14:02, HLA-B*08:01, HLA-C*07:02
RPMNRPTAL NP 1.9018 0.03207 (positive) 0.5629 (probable antigen) probable non-allergen non-toxin 100 non-homologue HLA-B*07:02, HLA-B*08:01, HLA-B*39:01, HLA-B*48:01, HLA-B*14:02, HLA-B*53:01, HLA-B*35:01
NPHAQGIAL GP 1.5028 0.10415 (positive) 1.0162 (probable antigen) probable non-allergen non-toxin 100 non-homologue HLA-B*39:01, HLA-B*35:01, HLA-B*15:02, HLA-B*07:02
FTYNLTNLV VP40 1.2927 0.00609 (positive) 0.7288 (probable antigen) probable non-allergen non-toxin 100 non-homologue HLA-A*02:01, HLA-A*68:02, HLA-A*02:06, HLA-A*01:01, HLA-A*26:01, HLA-B*51:01, HLA-C*06:02, HLA-C*15:02, HLA-B*46:01
RTTAPAAAF VP35 1.4688 0.13388 (positive) 0.4463 (probable antigen) probable non-allergen non-toxin 100 non-homologue HLA-A*32:01, HLA-B*58:01, HLA-B*57:01, HLA-B*07:02, HLA-C*03:03, HLA-B*15:01, HLA-B*35:01
SLTCAGIRK VP30 1.1697 0.17091 (positive) 1.3530 (probable antigen) probable non-allergen non-toxin 100 non-homologue HLA-A*03:01, HLA-A*11:01
ISPNLLGIY VP24 1.4959 0.07501 (positive) 1.0528 (probable antigen) probable non-allergen non-toxin 100 non-homologue HLA-A*30:02, HLA-A*01:01, HLA-A*26:01, HLA-B*46:01
a

MHC-I alleles with percentile rank ≤2 were taken.