TABLE I -.
Groups | Right lung | Left lung | |
---|---|---|---|
Healthy | 268 ± 24 | 423 ± 54 | |
Sacrifice 6 h | Vehicle | 2994 ± 496*,° | 1148 ± 193 |
Post-Hex | 1585 ± 316 | 1380 ± 262 | |
Pre-Hex | 1647 ±315 | 1013 ± 294 | |
Sacrifice 24 h | Vehicle | 2891 ± 289** | 773 ± 103 |
Post-Hex | 2145 ± 266°° | 616 ± 70 | |
Pre-Hex | 2364 ± 296# | 521 ± 90 |
In the right lung: ANOVA in Sacrifice 6 h experiment p<0.01, Tukey post hoc test; *p<0.01 vs. Healthy, °p<0.05 vs. Post-Hex; ANOVA in Sacrifice 24 h experiment p<0.01, Tukey post hoc test; **p<0.01 vs. Healthy, °°p<0.01 vs. Healthy, #p<0.01 vs. Healthy. In the left lung: ANOVA p = ns. Healthy: no surgical interventions or treatment (n = 5); Vehicle: HCl instillation + vehicle treatment (n = 8); Post-Hex: HCl instillation + Hexarelin treatment (n = 8); Pre-Hex: Hexarelin pretreatment + HCl instillation (n = 8).
ANOVA = analysis of variance; BAL = bronchoalveolar lavage; BCA = bicinchoninic acid.