TABLE 1.

Sensitivity analysis of childhood obesity and stroke in MR analysis.

Method	SNP(n)	Cochran’s Q	HT(p)	Intercept	PT(p)	RSSobs	GT(p)
Stroke				-0.0075	0.57	18.9	0.31
MR–Egger	14	13.8	0.32
IVW method	14	14.2	0.36
IS				-0.0054	0.69	17.5	0.39
MR–Egger	14	12.5	0.40
IVW method	14	12.7	0.47
LAS				-0.0018	0.97	24.6	0.12
MR–Egger	14	20.2	0.06
IVW method	14	20.2	0.09
CES				0.0208	0.63	38.3	0.003
MR–Egger	13	30.0	0.003
IVW method	13	30.7	0.004
SVS					0.40	28.9	0.04
MR–Egger	14	22.8	0.03	0.0308
IVW method	14	24.2	0.03
ICH				−0.0379	0.66	12.2	0.65
MR–Egger	13	8.5	0.96
IVW method	13	8.5	0.70

Abbreviation: IVW, inverse-variance-weighted; MR, Mendelian randomization; SNP, single nucleotide polymorphism; HT, heterogeneity test; PT, pleiotropy test; IS, ischemic stroke; LAS, large vessel ischemic stroke; CES, cardioembolic ischemic stroke; SVS, small vessel ischemic stroke; ICH, intracerebral hemorrhage; GT, MR-PRESSO Global Test.