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. 2021 Nov 16;60(47):3566–3581. doi: 10.1021/acs.biochem.1c00465

Figure 7.

Figure 7

Sticker clustering tunes intradroplet organization. (A) Assortativity, a measure of the spatial mixing between stickers and spacers, is measured for the entire system as a function of sticker strength, spacer strength, and sticker clustering. For each system, the phase boundary is shown as a dashed line for reference. For the well-clustered sequences, significant deviations from a value of 0 are observed. (B) To understand the origins of these large assortativity values, we generated snapshots from distinct regions in panel A (orange beads are stickers, and black beads spacers). These revealed the intradroplet organization of stickers into local clusters and subdomains. For sequences with the most well-clustered stickers, we observe an assortativity of >0 at subsaturating concentrations due to the presence of small labile clusters.