Table 2.

Rate advancement periods analyses

	RAPs, years (95% CI)
	Not meeting the recommendations		Meeting the recommendations
	< 300 MET/min/week	300–599 MET/min/week	600–899 MET/min/week	900–1199 MET/min/week	≥ 1200 MET/min/week
Dementia incidence	0 (Ref.)	− 4.40 (− 7.59; − 2.00)	− 7.89 (− 11.6; − 5.38)	− 9.62 (− 13.5; − 6.87)	− 12.3 (− 16.2; − 9.94)
Alzheimer’s disease incidence	0 (Ref.)	− 3.76 (− 10.2; 0.57)	− 5.87 (− 12.3; − 1.34)	− 7.74 (− 15.2; − 2.78)	− 9.25 (− 16.5; − 4.50)
Vascular dementia incidence	0 (Ref.)	− 4.16 (− 21.6; 2.94)	− 7.59 (− 27.5; 0.50)	− 16.2 (− 45.6; − 4.07)	− 12.3 (− 34.6; − 3.33)

All analyses were performed excluding participants with all-cause dementia and neurological disorders at baseline. Analyses were adjusted by age, sex, deprivation, ethnicity, education, morbidity count, BMI, smoking, alcohol intake, fruit and vegetable, total fish, red meat, and processed meat intake, log reaction time and log visual memory. Individuals who performed < 150 min/week were used as the reference group. MET, metabolic equivalent tasks