Table 1.

Passive neuronal properties and kinetics for mEPSC experiments

Experimental condition	Frequency (Hz)	Rin (MΩ)	Vm (mV)	Rise time (ms)	Decay τ (ms)
Figure 2 a
NT	4.13 ± 0.45	151 ± 7	−74 ± 2	0.56 ± 0.02	2.97 ± 0.12
IP: CNO	3.32 ± 0.47	172 ± 12	−77 ± 2	0.56 ± 0.01	2.72 ± 0.11
IP: DR + CNO	4.59 ± 0.41	176 ± 10	−73 ± 2	0.56 ± 0.02	2.72 ± 0.09
DW: CNO	4.13 ± 0.45	189 ± 7	−81 ± 1	0.53 ± 0.01	2.51 ± 0.07
DW: DR + CNO	4.19 ± 0.46	188 ± 7	−79 ± 2	0.54 ± 0.01	2.42 ± 0.06
Figure 3 b
CT+	1.54 ± 0.18	184 ± 10	−79 ± 1	0.57 ± 0.02	3.26 ± 0.16
CT–	2.33 ± 0.24	202 ± 7	−82 ± 1	0.56 ± 0.01	2.79 ± 0.10
GFP	1.99 ± 0.28	171 ± 8	−81 ± 1	0.59 ± 0.02	3.00 ± 0.11
Figure 5 c
Shk3 KO: NT	4.09 ± 0.41	192 ± 9	−79 ± 2	0.53 ± 0.01	2.59 ± 0.08
Shk3 KO: CNO	4.30 ± 0.37	206 ± 6	−83 ± 1	0.51 ± 0.01	2.51 ± 0.06
Shk3 KO: DR + CNO	4.95 ± 0.47	209 ± 10	−82 ± 2	0.56 ± 0.01	2.60 ± 0.08
Figure 7 d
NT	2.98 ± 0.25	146 ± 7	−80 ± 2	0.57 ± 0.01	3.09 ± 0.08
24 h	3.37 ± 0.27	152 ± 8	−78 ± 2	0.59 ± 0.01	3.04 ± 0.07
48 h	1.90 ± 0.10	157 ± 8	−83 ± 1	0.56 ± 0.02	2.80 ± 0.10

R_in, input resistance; V_m, resting membrane potential; IP, intraperitoneal injection; Shk3, Shank3.

^aMultigroup comparison (NT; IP: CNO; IP: DR + CNO): frequency, p = 0.054; R_in, p = 0.2016; V_m, p = 0.4854; rise time, p = 0.8648; decay τ, p = 0.1773. Two-group comparison (DW: CNO; DW: DR + CNO): frequency, p = 0.2366; R_in, p = 0.9982; V_m, p = 0.5476; rise time, p = 0.4422; decay τ, p = 0.7535.

^bMultigroup comparison (CT⁺, CT^–, GFP): frequency, p = 0.0510; R_in, p = 0.3211; V_m, p = 0.1993; rise time, p = 0.3189; decay τ, p = 0.2015.

^cMultigroup comparison (Shk3 KO: NT; Shk3 KO: CNO; Shk3 KO: DR + CNO): frequency, p = 0.4776; R_in, p = 0.345; V_m, p = 0.1637; rise time, p = 0.1724; decay τ, p = 0.8728.

^dMultigroup comparison (NT, 24 h, 48 h): frequency, p = 0.053; R_in, p = 0.1849; V_m, p = 0.1780; rise time, p = 0.0615; decay τ, p = 0.057.