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. 2021 Dec 1;41(48):9971–9987. doi: 10.1523/JNEUROSCI.0378-21.2021

Table 8.

Summary of week 1 neuro-motor reflexes, behavioral maturation, and attentiona

MIA (n = 14)
Control (n = 14)
p b
Mean (SD) Median [range] Mean (SD) Median [range]
Age (d) 7.0 (0.7) 7.0 [6.0-8.0] 6.9 (0.6) 7.0 [6.0-8.0] 0.95
Weight (kg)c 0.5 (0.1) 0.5 [0.5-0.7] 0.6 (0.1) 0.6 [0.4-0.7] 0.49
Gestation length (d) 168 (4) 167 [162-175] 167 (4) 167 [160-177] 0.97
Visual orientation 1.3 (0.6) 1.3 [0-2] 1.7 (0.4) 1.8 [1-2] 0.14
Visual follow 0.9 (0.4) 1.0 [0.5-1.5] 1.1 (0.6) 1.0 [0-2] 0.23
Head posture 2.0 (0.0) 2.0 [2-2] 2.0 (0.0) 2.0 [2-2] 1.00
Coordination 0.8 (0.8) 0.8 [0-2] 0.7 (0.7) 0.8 [0-2] 0.96
Spontaneous crawl 1.1 (0.7) 1.0 [0-2] 0.9 (0.7) 1.0 [0-2] 0.38
Rooting 0.6 (0.9) 0.0 [0-2] 0.4 (0.7) 0.0 [0-2] 0.78
Righting 1.9 (0.5) 2.0 [0-2] 1.9 (0.5) 2.0 [0-2] 1.00
Placing 1.1 (0.8) 1.0 [0-2] 0.8 (0.8) 0.8 [0-2] 0.36
Moro reflexd 1.8 (0.3) 2.0 [1-2] 1.7 (0.4) 2.0 [1-2] 0.76
Predominant state 0.9 (0.5) 1.0 [0-2] 0.6 (0.6) 0.5 [0-2] 0.19
Consolability 0.5 (0.7) 0.0 [0-2] 0.3 (0.6) 0.0 [0-1.5] 0.36

aAll animals were rated with a score from 0 to 2 (0 = reflex absent; 0.5 = reflex slightly developed or present; 1 = partially present or partially developed; 1.5 = mostly present or developed; 2 = reflex present or fully developed). Predominant state: 0 = calm, alert, aware; 0.5 = mostly calm with slight agitation; 1 = alert but agitated for no more than half the examination; 1.5 = agitated for more than half the examination; 2 = extremely agitated throughout entire examination. Consolability: 0 = quickly consoled when picked up following examination; 0.5 = consoled after brief period of holding and swaddling; 1 = infant consoled only after prolonged holding, swaddling, rocking, and/or stroking; 1.5 = brief moments of consolation and quiet after prolonged holding; 2 = inconsolable.

bFrom Wilcoxon two-sample exact tests.

cData missing for 2 animals in MIA group.

dData missing for 1 animal in MIA group.