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. 2021 Nov 18;9:775507. doi: 10.3389/fcell.2021.775507

TABLE 1.

Target genes of p53 involved in mTOR signaling.

Targets Position Sequence Refs
REDD1 –601 ∼ –582 AAA​CAA​GTC​TTT​CCT​TGA​TC Ellisen et al. (2002)
LKB1 –108 ∼ –88 AAC​CAA​CGG​GTG​GGC​ACG​TCG Co et al. (2014); Xie et al. (2017)
AMPKβ Exon 1 GTT​CTT​GCC​GCG​GCT​TGC​CT Feng et al. (2007)
TSC2 Intron 2a AGGCTAGTCTGAAACTCCTGGGCTGACGTGACGGGCATGGTGGCACATGCCT Feng et al. (2007)
Intron 2b
Intron 11 TAACAAGCTCGGGGCTAGCCC
PTEN –1190 ∼ –1157 GAGCAAGCCCCAGGCAGCTACACTGGGCATGCTC Stambolic et al. (2001)
Sestrin1 (PA26) –1241 ∼ –1222 GGA​CAA​GTC​TCC​ACA​AGT​CA Velasco-Miguel et al. (1999)
Sestrin2 (Hi95) Not identified Not identified Budanov et al. (2002)
mTOR 0.5 kb upstream promoter Not identified Ge et al. (2019)
Rictor 0.5 kb upstream promoter Not identified Ge et al. (2019)
DEPTOR –196 ∼ –169 GCTCAAGTTTCTGGGGCCGGACTAGCCC Cui et al. (2020a)