Table 3.

Univariate and multivariate logistic regression analysis of factors associated with unfavorable outcomes in the whole population

Variable	Univariate analysis		Multivariate analysis
	OR (95% CI)	P value	OR (95% CI)	P value
In-hospital death
Age (× 10 years)	2.42 (1.57–3.73)	< 0.001	2.33 (1.50–3.60)	0.002
Sex (male)	0.82 (0.43–1.54)	0.531
BMI (kg/m2)	1.01 (0.88–1.17)	0.845
Age-adjusted Charlson’s score	1.07 (0.95–1.21)	0.257
Glucose at entry (× 10 mg/dl)	1.03 (0.99–1.06)	0.113
Diabetes	0.52 (0.27–1.02)	0.056	0.70 (0.35–1.42)	0.327
Stress hyperglycemia (SHR ≥ 1.2)	3.20 (1.39–7.40)	0.007	2.94 (1.24–6.95)	0.014
Insulin treatment	1.13 (0.60–2.12)	0.711
Basal-bolus treatment*	0.60 (0.23–1.55)	0.294
Complications (all events)
Age (× 10 years)	1.41 (1.14–1.75)	0.002	1.44 (1.15–1.81)	0.013
Sex (male)	0.85 (0.54–1.34)	0.490
BMI (kg/m2)	1.05 (0.96–1.14	0.267
Age-adjusted Charlson’s score	1.06 (0.97–1.17)	0.215
Glucose at entry (× 10 mg/dl)	1.03 (1.00–1.05)	0.039	1.02 (1.00–1.05)	0.097
Diabetes	1.07 (0.68–1.68)	0.778
Stress hyperglycemia (SHR ≥ 1.2)	2.41 (1.43–4.06)	0.001	2.07 (1.19–3.59)	0.010
Insulin treatment	1.45 (0.92–2.29)	0.105
Basal-bolus treatment*	0.64 (0.34–1.23)	0.182
Systemic infections°
Age (× 10 years)	1.16 (0.91–1.47)	0.220
Sex (male)	0.89 (0.51–1.54)	0.672
BMI (kg/m2)	1.01 (0.92–1.11)	0.869
Age-adjusted Charlson’s score	1.03 (0.93–1.15)	0.548
Glucose at entry (× 10 mg/dl)	1.01 (0.98–1.04)	0.563
Diabetes	1.15 (0.67–1.98)	0.618
Stress hyperglycemia (SHR ≥ 1.2)	2.36 (1.24–4.50)	0.009	2.36 (1.24–4.50)	0.009
Insulin treatment	1.21 (0.70–2.09)	0.496
Basal-bolus treatment*	0.61 (0.28–1.30)	0.198

*Limited to insulin-treated patients

°In patients without infection at admission (n = 260)