Fig 3. Differences in 25(OH)D levels between carriers and non-carriers of CYP related MS risk alleles.

25(OH)D levels at baseline (N = 26) (A) and after 48 weeks vitamin D₃ supplementation (N = 20) (B), compared between non-carriers (left group) and carriers (right group) of the rs12368653 and rs2248359 risk alleles. P-value shown is calculated using a Mann-Whitney U test. Triangles indicate calculated data, derived from immunoassay values to replace missing values from the LC-MS/MS method.