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. 2021 Dec 2;16(12):e0260705. doi: 10.1371/journal.pone.0260705

Fig 4. Ventilation parameters and inflammatory status after lung procurement.

Fig 4

Lungs were procured from either healthy rats (experimental group 1) or rats subjected to 3 hours of brain death (BD, experimental group 2). (A) Pulmonary Inspiratory Pressure (PIP) required to maintain tidal volume at 7 ml/kg of bodyweight and dynamic compliance (Cdyn) of healthy donor lungs 1) versus donor lungs subjected to 3 hours of BD, at time of lung procurement. (B) Pro-inflammatory gene expressions of TNF-α, IL-1β, IL-6, MCP-1 and C3 of healthy donor lungs versus donor lungs subjected to 3 hours of BD. ** p<0.01 in healthy donor lungs versus lungs from brain-dead donors.