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. 2021 Dec 2;16(12):e0260705. doi: 10.1371/journal.pone.0260705

Fig 6. Ventilation and perfusion performance during ex vivo lung perfusion.

Fig 6

Lungs from healthy donor rats or rats subjected to 3 hours of brain death (BD) and 1 hour cold storage (CS) were ex vivo perfused for 6 hours (EVLP, experimental group 3 and 4). (A) Positive Inspiratory Pressure (PIP) required to maintain tidal volume at 7 ml/kg of bodyweight over time, during EVLP. (B) Dynamic compliance (Cdyn) of donor lungs over time, during EVLP. (C) Oxygenation capacity of donor lungs as reflected by PaO2/FiO2 ratio. (D) Perfusion flow of donor lungs over time, during EVLP. * p<0.05 in healthy donor lungs versus lungs from brain-dead donors subjected to EVLP. ** p<0.01 in healthy donor lungs versus lungs from brain-dead donors subjected to EVLP.