Table 1. Descriptive characteristics of studied samples through 3 waves of examinations.
| Characteristics | Wave 1 (2002–2005) n = 9,218 | Wave 2 (2006–2008) n = 3,379 | Wave 3 (2015–2017) n = 3,785 | |||
|---|---|---|---|---|---|---|
| men | women | men | women | men | Women | |
| Observed, n | 4199 | 5019 | 1361 | 2018 | 1451 | 2334 |
| Time since W1, years | 0.0 | 0.0 | 2.95 | 3.33 | 12.2 | 12.4 |
| Age, years | 58.2 (6.94) | 57.9 (7.04) | 60.8 (6.91) | 61.0 (6.85) | 68.9 (6.89) | 69.4 (6.80) |
| TC, mmol/l | 6.01 (1.19) | 6.52 (1.30) | 5.55 (0.99) | 6.05 (1.09) | 5.18 (1.13) | 5.65 (1.18) |
| LDL-C, mmol/l | 3.84 (1.06) | 4.24 (1.17) | 3.52 (0.88) | 3.89 (0.99) | 3.29 (0.99) | 3.58 (1.08) |
| HDL-C, mmol/l | 1.50 (0.38) | 1.56 (0.35) | 1.42 (0.35) | 1.51 (0.33) | 1.24 (0.38) | 1.38 (0.38) |
| TG, mmol/l | 1.28 (0.97–1.74) | 1.38 (1.06–1.85) | 1.20 (0.92–1.58) | 1.27 (0.98–1.68) | 1.21 (0.86–1.74) | 1.30 (0.97–1.80) |
| SBP, mmHg | 144.2 (23.5) | 144.5 (26.1) | 145.2 (23.3) | 146.8 (25.3) | 146.6 (20.5) | 144.8 (21.6) |
| DBP, mmHg | 90.8 (13.4) | 90.5 (13.5) | 99.6 (13.0) | 90.3 (13.4) | 85.8 (11.8) | 82.2 (10.8) |
| BMI, kg/m 2 | 26.6 (4.44) | 30.2 (5.72) | 27.0 (4.45) | 30.3 (5.48) | 27.8 (4.61) | 30.5 (5.72) |
| LLT, n (%) * | 130/420 (31.0) | 208/999 (20.8) | 77/366 (21.0) | 188/1013 (18.6) | 161/348 (46.3) | 573/1211 (47.3) |
| Smoking, n (%) | ||||||
| Non smokers | 1072 (25.5) | 4275 (85.2) | 381 (28.0) | 1735 (86.0) | 438 (30.2) | 2041 (87.4) |
| Ex-smokers | 1036 (24.7) | 222 (4.4) | 409 (30.1) | 105 (5.2) | 393 (27.1) | 100 (4.3) |
| Regular smokers | 2091 (49.8) | 522 (10.4) | 571 (42.0) | 178 (8.6) | 620 (42.7) | 193 (8.3) |
| Alcohol intake, n (%) | ||||||
| Non drinkers | 829 (19.8) | 1822 (36.4) | 243 (17.9) | 624 (30.9) | 255 (17.67) | 705 (30.2) |
| Moderate drinkers | 2954 (70.5) | 3154 (62.9) | 979 (72.0) | 1380 (68.4) | 1046 (72.2) | 1612 (69.1) |
| Heavy drinkers | 409 (9.8) | 36 (0.7) | 137 (10.1) | 12 (0.6) | 148 (10.2) | 15 (0.6) |
| Education, n (%) | ||||||
| Primary | 470 (11.2) | 474 (9.4) | 64 (4.7) | 104 (5.2) | 82 (5.7) | 151 (6.5) |
| Secondary | 917 (21.6) | 1534 (30.6) | 275 (20.2) | 587 (29.1) | 323 (22.3) | 705 (30.2) |
| Vocational | 1473 (35.1) | 1685 (33.6) | 484 (35.6) | 720 (35.7) | 465 (32.0) | 754 (32.3) |
| University | 1339 (31.9) | 1326 (26.4) | 538 (39.6) | 607 (30.1) | 581 (40.0) | 724 (31.0) |
| Marital status, n (%) | ||||||
| Single | 507 (12.1) | 2031 (40.5) | 139 (10.2) | 764 (37.9) | 132 (9.1) | 855 (36.6) |
| Married /cohabiting | 3692 (87.9) | 2988 (59.5) | 1222 (89.8) | 1254 (62.1) | 1319 (90.9) | 1479 (63.4) |
| History of CVD, n (%) | 987 (23.5) | 1001 (19.9) | 309 (22.7) | 410 (19.9) | 266 (18.3) | 393 (16.8) |
| History of chronic diseases, n (%) | 1113 (26.5) | 1327 (26.4) | 361 (25.8) | 513 (25.4) | 302 (20.8) | 519 (22.2) |
| CVD death during follow-up -, n (%) | 374 (8.9) | 159 (3.3) | 69 (5.4) | 24 (1.2) | - | - |
| All causes death during follow-up **, n (%) | 839 (20.0) | 365 (7.3) | 141 (10.4) | 57 (2.8) | - | - |
Values are mean (sd) or n (%)
* LLT—lipid lowering treatment among those with history of dyslipidemia
** Mortality follow-up limited to 2011.