Table 2. Baseline total cholesterol, LDL-C, HDL-C and triglycerides (intercept) and change in LDL-C, HDL-C and triglycerides per year (slope) in the 5-yr cohorts (unadjusted).
Age range in W1 | TC | LDL-C | ||||||
coeff. | SE | p-value | coeff. | SE | p-value | |||
Intercept | Estimate (mmol/l) | 45–49 (ref) | 5.94 | 0.031 | <0.001 | 3.76 | 0.028 | <0.001 |
Difference compared to reference group | 50–54 | 0.217 | 0.042 | <0.001 | 0.181 | 0.038 | <0.001 | |
55–59 | 0.344 | 0.041 | <0.001 | 0.284 | 0.037 | <0.001 | ||
60–64 | 0.492 | 0.043 | <0.001 | 0.439 | 0.038 | <0.001 | ||
65–69 | 0.421 | 0.041 | <0.001 | 0.379 | 0.037 | <0.001 | ||
Slope | Estimate (mmol/l/year) | 45–49 (ref) | -0.026 | 0.003 | <0.001 | -0.014 | 0.003 | <0.001 |
Difference compared to reference group | 50–54 | -0.025 | 0.005 | <0.001 | -0.021 | 0.004 | <0.001 | |
55–59 | -0.047 | 0.005 | 0.001 | -0.041 | 0.004 | <0.001 | ||
60–64 | -0.065 | 0.005 | <0.001 | -0.053 | 0.004 | <0.001 | ||
65–69 | -0.069 | 0.006 | <0.001 | -0.059 | 0.005 | <0.001 | ||
HDL-C | TG | |||||||
coeff. | SE | p-value | coeff. | SE | p-value | |||
Intercept | Estimate (mmol/l) | 45–49 (ref) | 1.54 | 0.010 | <0.001 | 1.40 | 0.020 | <0.001 |
Difference compared to reference group | 50–54 | -0.004 | 0.012 | 0.713 | 0.089 | 0.027 | 0.001 | |
55–59 | -0.011 | 0.012 | 0.339 | 0.150 | 0.027 | <0.001 | ||
60–64 | -0.017 | 0.012 | 0.173 | 0.152 | 0.027 | <0.001 | ||
65–69 | -0.029 | 0.012 | 0.013 | 0.161 | 0.026 | <0.001 | ||
Slope | Estimate (mmol/l/year) | 45–49 (ref) | -0.019 | 0.001 | <0.001 | 0.012 | 0.002 | <0.001 |
Difference compared to reference group | 50–54 | -0.002 | 0.002 | 0.178 | -0.006 | 0.003 | 0.053 | |
55–59 | 0.001 | 0.002 | 0.761 | -0.015 | 0.003 | <0.001 | ||
60–64 | 0.002 | 0.002 | 0.368 | -0.028 | 0.003 | <0.001 | ||
65–69 | 0.003 | 0.002 | 0.101 | -0.030 | 0.003 | <0.001 |