Table 3. Baseline total cholesterol, LDL-C, HDL-C and triglycerides (intercept) and change in LDL-C, HDL-C and triglycerides per year (slope) in the 5-yr cohorts (adjusted*).
Age range in W1 | TC | LDL-C | ||||||
coeff. | SE | p-value | coeff. | SE | p-value | |||
Intercept | Estimate (mmol/l) | 45–49 (ref) | 5.64 | 0.033 | <0.001 | 3.54 | 0.030 | <0.001 |
Difference compared to reference group | 50–54 | 0.239 | 0.041 | <0.001 | 0.197 | 0.037 | <0.001 | |
55–59 | 0.362 | 0.040 | <0.001 | 0.298 | 0.036 | <0.001 | ||
60–64 | 0.514 | 0.042 | <0.001 | 0.456 | 0.037 | <0.001 | ||
65–69 | 0.447 | 0.040 | <0.001 | 0.397 | 0.036 | <0.001 | ||
Slope | Estimate (mmol/l/year) | 45–49 (ref) | -0.024 | 0.004 | <0.001 | -0.012 | 0.004 | 0.020 |
Difference compared to reference group | 50–54 | -0.026 | 0.005 | <0.001 | -0.021 | 0.004 | <0.001 | |
55–59 | -0.047 | 0.005 | 0.001 | -0.041 | 0.004 | <0.001 | ||
60–64 | -0.066 | 0.005 | <0.001 | -0.054 | 0.004 | <0.001 | ||
65–69 | -0.071 | 0.005 | <0.001 | -0.060 | 0.004 | <0.001 | ||
Age range in W1 | HDL-C | TG | ||||||
coeff. | SE | p-value | coeff. | SE | p-value | |||
Intercept | Estimate (mmol/l) | 45–49 (ref) | 1.50 | 1.34 | 1.34 | 1.34 | 0.030 | <0.001 |
Difference compared to reference group | 50–54 | -0.011 | 0.091 | 0.091 | 0.091 | 0.037 | <0.001 | |
55–59 | -0.007 | 0.150 | 0.150 | 0.150 | 0.036 | <0.001 | ||
60–64 | -0.012 | 0.154 | 0.154 | 0.154 | 0.037 | <0.001 | ||
65–69 | -0.025 | 0.163 | 0.163 | 0.163 | 0.036 | <0.001 | ||
Slope | Estimate (mmol/l/year) | 45–49 (ref) | -0.020 | 0.013 | 0.013 | 0.013 | 0.004 | 0.020 |
Difference compared to reference group | 50–54 | -0.002 | -0.006 | -0.006 | -0.006 | 0.004 | <0.001 | |
55–59 | 0.001 | -0.015 | -0.015 | -0.015 | 0.004 | <0.001 | ||
60–64 | 0.002 | -0.028 | -0.028 | -0.028 | 0.004 | <0.001 | ||
65–69 | 0.003 | -0.031 | -0.031 | -0.031 | 0.004 | <0.001 |
*Adjusted by sex and lipid-lowering treatment.