Table 4. Baseline total cholesterol, LDL-C, HDL-C and triglycerides (intercept) and change in LDL-C, HDL-C and triglycerides per year (slope) in the 5-yr cohorts (^* multivariable adjusted).

		Age range in W1	TC			LDL-C
			coeff.	SE	p-value	coeff.	SE	p-value
Intercept	Estimate (mmol/l)	45–49 (ref)	5.35	0.058	<0.001	3.37	0.052	<0.001
	Difference compared to reference group	50–54	0.228	0.043	<0.001	0.190	0.038	<0.001
		55–59	0.354	0.042	<0.001	0.284	0.038	<0.001
		60–64	0.520	0.045	<0.001	0.445	0.040	<0.001
		65–69	0.482	0.045	<0.001	0.420	0.040	<0.001
Slope	Estimate (mmol/l/year)	45–49 (ref)	-0.027	0.003	<0.001	-0.011	0.003	0.002
	Difference compared to reference group	50–54	-0.025	0.005	<0.001	-0.021	0.004	<0.001
		55–59	-0.045	0.005	<0.001	-0.039	0.004	<0.001
		60–64	-0.064	0.005	<0.001	-0.052	0.004	<0.001
		65–69	-0.068	0.007	<0.001	-0.057	0.005	<0.001
		Age range in W1	HDL-C			TG
			coeff.	SE	p-value	coeff.	SE	p-value
Intercept	Estimate (mmol/l)	45–49 (ref)	1.47	1.11	1.11	1.11	0.052	<0.001
	Difference compared to reference group	50–54	0.020	0.059	0.059	0.059	0.038	<0.001
		55–59	0.021	0.098	0.098	0.098	0.038	<0.001
		60–64	0.014	0.131	0.131	0.131	0.040	<0.001
		65–69	0.017	0.094	0.094	0.094	0.040	<0.001
Slope	Estimate (mmol/l/year)	45–49 (ref)	-0.018	0.008	0.008	0.008	0.003	0.002
	Difference compared to reference group	50–54	-0.002	-0.005	-0.005	-0.005	0.004	<0.001
		55–59	-0.001	-0.011	-0.011	-0.011	0.004	<0.001
		60–64	-0.000	-0.024	-0.024	-0.024	0.004	<0.001
		65–69	0.001	-0.023	-0.023	-0.023	0.005	<0.001

*Adjusted by sex, lipid-lowering treatment, smoking, BMI, alcohol intake, education, marital status, CVD mortality, all-cause mortality.