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. 2021 Nov 18;8:787866. doi: 10.3389/fcvm.2021.787866

Table 2.

Clinical outcomes between the patients with atrial fibrillation and atrial flutter not receiving warfarin therapy before and after PSM.

Variable Before PSM After PSM
AF (n = 232,425) AFL (n = 7,569) P-value AF (n = 30,276) AFL (n = 7,569) P-value
Dementia
    Number of events, n (%) 22,833 (9.82) 521 (6.88) 2,435 (8.04) 521 (6.88)
    Incidence density§ 3.04 (3.00–3.08) 2.05 (1.87–2.22) 2.33 (2.24–2.43) 2.05 (1.87–2.22)
    Hazard ratio (95% CI) 1.52 (1.39–1.66) Reference <0.0001 1.14 (1.04–1.25) Reference 0.0064
Ischemic stroke
    Number of events, n (%) 18,475 (7.95) 297 (3.92) 2,095 (6.92) 297 (3.92)
    Incidence density§ 2.54 (2.50–2.58) 1.18 (1.04–1.31) 2.07 (1.98–2.16) 1.18 (1.04–1.31)
    Hazard ratio (95% CI) 2.15 (1.92–2.42) Reference <0.0001 1.76 (1.56–1.98) Reference <0.0001

AF, atrial fibrillation; AFL, atrial flutter; PSM, propensity score matching.

§ Incidence density: number of events per 100 person-years.