Table 4.
Clinical outcomes between the patients with atrial fibrillation and atrial flutter before and after PSM (without history of stroke).
| Variable | Before PSM | After PSM | ||||
|---|---|---|---|---|---|---|
| AF (n = 200,646) | AFL (n = 6,683) | P-value | AF (n = 26,732) | AFL (n = 6,683) | P-value | |
| Dementia | ||||||
| Number of events, n (%) | 18,693 (9.32) | 431 (6.45) | 1,983 (7.42) | 431 (6.45) | ||
| Incidence density§ | 2.77 (2.73–2.81) | 1.85 (1.67–2.02) | 2.11 (2.02–2.20) | 1.85 (1.67–2.02) | ||
| Hazard ratio (95% CI) | 1.54 (1.40–1.69) | Reference | <0.0001 | 1.15 (1.03–1.27) | Reference | 0.0098 |
| Ischemic stroke | ||||||
| Number of events, n (%) | 15,119 (7.54) | 232 (3.47) | 1,661 (6.21) | 232 (3.47) | ||
| Incidence density§ | 2.31 (2.28–2.35) | 1.00 (0.87–1.13) | 1.82 (1.73–1.91) | 1.00 (0.87–1.13) | ||
| Hazard ratio (95% CI) | 2.32 (2.04–2.64) | Reference | <0.0001 | 1.82 (1.59–2.09) | Reference | <0.0001 |
AF, atrial fibrillation; AFL, atrial flutter; PSM, propensity score matching.
§ Incidence density: number of events per 100 person-years.