Table 2. Odds ratio (OR) and 95% confidence interval (CI) for colorectal cancer risk by serum C-reactive protein (CRP) level for the nested case-control study in the JACC Study.

Study cases	Ranks for serum CRP level	Ranges (mg/L)			No.		Crude			Adjusted*
					Cases	Controls	OR	95% CI	p for trend	OR	95% CI	p for trend
Overall for colorectal cancer	T1 (lowest)		-	0.26	47	110	1.00	(reference)		1.00	(reference)
	T2	0.27	-	0.80	46	107	1.00	0.60-1.66		1.13	0.66-1.94
	T3 (highest)	0.81	-		48	110	1.07	0.64-1.78	0.80	1.18	0.68-2.06	0.57
Incidence for colorectal cancer	T1 (lowest)		-	0.26	37	84	1.00	(reference)		1.00	(reference)
	T2	0.27	-	0.80	35	84	0.93	0.52-1.65		1.05	0.57-1.94
	T3 (highest)	0.81	-		32	83	0.91	0.50-1.66	0.77	0.97	0.51-1.83	0.98
Overall for colon cancer	T1 (lowest)		-	0.26	34	79	1.00	(reference)		1.00	(reference)
	T2	0.27	-	0.80	30	78	0.90	0.50-1.62		1.09	0.57-2.07
	T3 (highest)	0.81	-		37	80	1.16	0.64-2.08	0.61	1.42	0.73-2.74	0.29

*: Adjusted for smoking and alcohol consumption, and body mass index.