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. 2021 Nov 18;11:759497. doi: 10.3389/fonc.2021.759497

Table 4.

Correlation of PD1 and PDL1 gene expression with clinical parameters of squamous cell carcinoma lung cancer patients in the validation dataset.

PD1 PDL1
Variable Mean ± SD Median P-value a P-value b Mean ± SD Median P-value a P-value b
Gender Female 6.94 ± 0.12 6.93 Ref. Ref. 7.43 ± 0.66 7.21 Ref. Ref.
Male 6.93 ± 0.12 6.91 0.5671 0.4460 7.43 ± 0.67 7.23 0.9884 0.7380
Stage 1 6.96 ± 0.12 6.95 Ref. Ref. 7.34 ± 0.59 7.18 Ref. Ref.
2+3 6.92 ± 0.12 6.91 0.0003 0.0004 7.48 ± 0.71 7.28 0.0205 0.0736
Survival Alive 6.93 ± 0.13 6.92 Ref. Ref. 7.48 ± 0.69 7.26 Ref. Ref.
Dead 6.93 ± 0.12 6.92 0.8604 0.9513 7.38 ± 0.64 7.21 0.0988 0.0857

SD, standard deviation; Ref., reference group.

a

P value for Independent t-test.

b

P value for Mann-Whitney U test.

Bold face: statistically significant (P value<0.05).